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Am. J. Trop. Med. Hyg., s1-31(5), 1951, pp. 665-668
Copyright © 1951 by The American Society of Tropical Medicine and Hygiene

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Production of Polyvalent Antivenin against Trimeresurus Flavoviridis and Agkistrodon Blomhoffii Venoms1

Kenneth F. Burns2

1. Immunization of a horse with a mixture of Trimeresurus flavoviridis and Agkistrodon blomhoffii venoms resulted in the production of a highly satisfactory, potent polyvalent antivenin.
2. The antivenin titers against both venoms were high and exceeded minimal acceptable potency standards.
3. Seventy days were required for hypervenomization and the total dosage injected was 161.1 mgs. for each of the venoms employed.


1 From the Department of Virus and Rickettsial Diseases, 406th Medical General Laboratory, APO 500, c/o Postmaster, San Francisco, California.


2 Major, V. C., United States Army.






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Copyright © 1951 by the American Society of Tropical Medicine and Hygiene.