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The Blood and Bone Marrow Pattern in Sleeping Sickness in Portuguese Guinea¹

Blood and bone marrow cytologic studies were made on 32 cases of sleeping sickness seen in Portuguese Guinea.

The blood picture of African trypanosomiasis can be summarized as follows: slight microcytic normochromic anemia, moderate leukocytosis with an increase of the monocytes and lymphocytes, and neutropenia with a shift to the left of Schilling's hemogram. The number of platelets is normal. Hemoglobin breakdown is increased, serum iron normal or elevated, normal icterus index and normal or decreased fragility of the erythrocytes.

The bone marrow picture shows an increase of the erythroblastic series and a great number of immature megakaryocytes. Plasmocytes are slightly increased and Mott cells can be found.

¹ From the Department of Hematology and Protozoology of the Institute of Tropical Medicine, Lisbon.

² Professor of Hematology and Protozoology.

³ Assistant.