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The Treatment of Malaria

1. The immediate problem of malaria is one of therapeutics rather than sanitation.

2. The accepted death rate of 2.89 per cent in ordinary malaria, and 26.6 in pernicious malaria, deserves serious attention.

3. In a series of 8000 cases ocurring in tropical practice the mortality was reduced to 0.2 per cent for general malaria, and to 6 per cent for the malignant types.

4. The arsphenamines promptly abort acute attacks in all forms of malaria, and are specifics in the tertian field.

5. Neo-arsphenamine in concentrated solutions—as much as 0.9 gram in 2 cc.—fulfills all essential requirements of the higher dilutions. Technic of injection is given.

6. Neo-arsphenamine by rectum is efficacious.

7. Colloidal quinine (Colobiases de Quinine—Dausse), in doses of 1 grain (0.065), is therapeutically equivalent to 15 grains (1.0) of ordinary quinine salts, and is non-toxic.

8. Colloidal manganese and iron (Diéménal) is antiperiodic and reconstructive.

9. The management of acute, chronic, cachectic and pernicious malaria is outlined.

Received April 2, 1923.