HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Felsenfeld, O. Articles by Young, V. M. Search for Related Content PubMed Articles by Felsenfeld, O. Articles by Young, V. M.

Simultaneous Vaccination against Bacillary Dysentery and Cholera with Toxoid-Vaccine¹

This investigation was inaugurated by the Health Service of the Czechoslovak Army eight years ago, for the purpose of producing a reliable combined vaccine against cholera and dysentery, which might be used in the eventuality that troops would be stationed in areas where these diseases are prevalent. Due to events preceding the present holocaust the experiments were necessarily interrupted and reopened during recent years in the United States.

A vaccine was sought which would protect against infections with V. cholerae, Sh. dysenteriae and Sh. paradysenteriae Y, the latter being chosen because of its ability to confer partial immunity against the most common Shigella strains, namely Sh. paradysenteriae V, W and Z.

In order to determine which type of Sh. dysenteriae vaccine would confer maximum immunity, alcohol and heat killed organisms, and formolized and phenolized bacillary suspensions were tested. Organisms extracted with trichloracetic acid, formamate and diethylene glycol were utilized.

Received November 28, 1944.
¹ Read at the 40th Annual meeting of the American Society of Tropical Medicine, St. Louis, Mo., November 13–16, 1944.

² Present address: Mount Sinai Medical Research Foundation, Chicago (8), Ill.