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Am. J. Trop. Med., s1-25(2), 1945, pp. 129-136
Copyright © 1945 by American Journal of Tropical Medicine

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Observations on the Microfilaria of Onchocerca Volvulus with Silver Stains

William McKee German
From the Department of Pathology, College of Medicine, University Cincinnati, Cincinnati, Ohio

A silver stain is described which facilitates the demonstration of microfilaria in tissues. In addition, the stain reveals details not shown by routine procedures.

Additional study would suggest that the microfilaria leave the Onchocerca nodule by the perivascular tissue spaces and not through the capillaries themselves. Evidence is present to suggest that invasion of capillaries is blocked by prompt reaction and thrombosis and that the microfilaria may be destroyed in the ensuing reaction.

Received October 19, 1944.




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Copyright © 1945 by the American Society of Tropical Medicine and Hygiene.