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Am. J. Trop. Med., s1-21(4), 1941, pp. 589-595
Copyright © 1941 by American Journal of Tropical Medicine

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Spherule Formation in Culture by Coccidioides Immitis Rixford and Gilchrist, 18961

E. E. Baker AND E. M. Mrak
From the Department of Public Health and Preventive Medicine, Stanford University School of Medicine, San Francisco, California and the University of California, Berkeley, California

The formation, in culture, of structures resembling spherules has been described for Coccidioides immitis. Certain conditions concerned with their production have been discussed. It is suggested that spherules formed in culture represent a normal stage in the life cycle of the strains of Coccidioides immitis in which they were found.

Received November 1, 1940.
1 This study was financed by a grant from the Rosenberg Foundation.






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Copyright © 1941 by the American Society of Tropical Medicine and Hygiene.