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The 226 positive and 172 negative smears accruing during the daily (in some instances every second day) examination of the peripheral blood of fifty canaries mosquito-infected with Plasmodium cathemerium (Hartman) have been studied with the object of arranging them according to the time required to count a given number of asexual organisms. It was observed that the rate of progression and diminution in these infections occurred in such manner that a system of plus counting could be devised as follows.
1 The work was partially supported by a grant from the Committee on Therapeutic Research of the American Medical Association.
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