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Transmission of the Virus of Equine Encephalomyelitis Through Aedes Albopictus, Skuze

In 1933, it was shown by Kelser (1), at the Army Medical School, that a mosquito, Aedes aegypti, is capable of transmitting the virus of equine encephalomyelitis, western type, from infected guinea pigs to normal guinea pigs and to horses. This observation not only added another virus disease to those known to be transmissible by A. aegypti, but was the first demonstration of the conveyance of an essentially neurotropic virus by such a vector. In these experiments it was observed that the mosquitoes became infective after they had ingested the blood of guinea pigs into which virus had been inoculated 48 and 72 hours previously; that mosquitoes which fed on the same animals, 96 and 120 hours after the inoculation of the virus, did not always transmit the disease; and that others, which fed after 144 hours, failed to transmit the virus when tested later by allowing them to bite normal animals.

Received January 21, 1936.
¹ Major, Medical Corps, United States Army.

² Major, Veterinary Corps, United States Army.

³ Major, Medical Corps, United States Army.

⁴ With the technical assistance of Staff Sergeants George F. Luippold and Jesse F. Rhodes, Medical Department, United States Army.