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Am. J. Trop. Med. Hyg., 78(2), 2008, pp. 248-250
Copyright © 2008 by The American Society of Tropical Medicine and Hygiene

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SHORT REPORT


Rapid Control of Malaria by Means of Indoor Residual Spraying of Alphacypermethrin in the Democratic Republic of São Tomé and Príncipe

Lien Fen Tseng, Wen Chun Chang, Maria Conceição Ferreira, Cheng Hua Wu, Herodes Sacramento Rampão, AND Jih Ching Lien*
The Anti-Malaria Team of Taiwan, Medical Mission to São Tomé and Príncipe, São Tomé and Príncipe; Centro Nacional de Endemias (CNE), Democratic Republic of São Tomé and Príncipe; Institute of Preventive Medicine, National Defense Medical Center, Sanhsia, Taipei County, Taiwan 237

 

ABSTRACT

A nationwide yearly cycle of indoor residual spraying (IRS) with a pyrethroid, alphacypermethrin, at a dosage of 50 mg/m2 was instituted in 2004 in the Democratic Republic of São Tomé and Príncipe. Rates of IRS acceptance were high, varying from 82% to 95% for dwellings and outhouses. Epidemiologic surveys of the children < 9 years of age before and after the first IRS cycle revealed a rapid reduction in malaria. Overall prevalence of malaria parasitemia for all districts was lowered from 20.1% to 2.8% at 12 months after the first IRS and reached 0.7% at 8 months after the second IRS. Longer insecticidal persistence was found on wood than on cement with alphacypermethrin.

Received April 10, 2007. Accepted for publication September 28, 2007.

Acknowledgments: We are grateful to the Ministry of Foreign Affairs of Taiwan for financial support, to the International Cooperation and Development Fund of Taiwan (ICDF) for administrative support, and to the Center for Disease Control of Taiwan for technical assistance. Many thanks also go to the staff of CNE for their close cooperation in field operations, to the short-term assistants from the CDC of Taiwan for their technical assistance in the laboratory, and to Chang Chi Lin, the Department of Microbiology and Immunology, National Defense Medical Center, for his PCR tests to determine the vector mosquito identity and insecticide resistance.

* Address correspondence to Jih Ching Lien, Institute of Preventive Medicine, National Defense Medical Center, P.O. Box 90048-700 Sanhsia, Taipei County, Taiwan 237. E-mail: jihchinglien{at}gmail.com

Authors’ addresses: Lien Fen Tseng, Wen Chun Chang, Cheng Hua Wu, and Jih Ching Lien, The Anti-Malaria Team of Taiwan Medical Mission to São Tomé and Príncipe, C.P. 839, São Tomé e Prncipe. í Maria Conceição Ferreira and Herodes Sacramento Rampão, Centro Nacional de Endemias (CNE), República Democrática de São Tom é e Príncipe. Jih Ching Lien, Institute of Preventive Medicine, National Defense Medical Center, Sanhsia, Taipei County, Taiwan 237, Telephone: +886-2-25944651, Fax: +886-2-25947988, E-mail: jihchinglien{at}gmail.com.






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Copyright © 2008 by the American Society of Tropical Medicine and Hygiene.