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Am. J. Trop. Med. Hyg., 78(2), 2008, pp. 239-240
Copyright © 2008 by The American Society of Tropical Medicine and Hygiene

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CASE REPORT


Hyper-reactive Malarial Splenomegaly in a Patient with Human Immunodeficiency Virus

G. De Iaco, N. Saleri, F. Perandin, M. Gulletta, G. Ravizzola, N. Manca, L. Signorini, A. Matteelli*, K. Prestini, AND F. Castelli
Infectious and Tropical Medicine Institute, University of Brescia, Italy; Department of Laboratory Diagnosis, Section of Microbiology, University of Brescia, Spedali Civili, Italy

 

ABSTRACT

Both hyperreactive malarial splenomegaly (HMS) and HIV infection are highly prevalent in sub-Saharan Africa, but the inter-relationships between the two conditions are not clearly defined. Diagnosis of HMS is particularly difficult in HIV-infected patients, and detection of circulating malaria parasites by polymerase chain reaction (PCR) may represent a useful diagnostic tool.

Received August 7, 2006. Accepted for publication April 3, 2007.

* Address correspondence to Alberto Matteelli, Infectious and Tropical Medicine Institute, University of Brescia, Italy, Piazza Spedali Civili 1, 25100 Brescia, Italy. E-mail amatteelli{at}bsnet.it

Authors’ addresses: G. De Iaco, N. Saleri, M. Gulletta, L. Signorini, A. Matteelli, K. Prestini, and F. Castelli, Infectious and Tropical Medicine Institute, University of Brescia, Italy, Telephone: +39 030 399 5802, Fax: +39 030 303 061, E-mail: amatteelli{at}bsnet.it. F. Perandin, G. Ravizzola, and N. Manca, Department of Laboratory Diagnosis, Section of Microbiology, University of Brescia, Spedali Civili, Italy.

Reprint requests: Alberto Matteelli, Infectious and Tropical Medicine Institute, University of Brescia, Italy, Piazza Spedali Civili 1, 25100 Brescia, Italy. E-mail amatteelli{at}bsnet.it.






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Copyright © 2008 by the American Society of Tropical Medicine and Hygiene.