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Fatal Systemic Infection with Multifocal Liver and Lung Nodules Caused by Brucella abortus

We experienced a fatal case caused by Brucella abortus with multifocal necrosis confirmed by culture and polymerase chain reaction. Our case highlights that the clinician should be aware of the potential for fatality when a patient with brucellosis shows dissemination of abscess or nodules with no calcification in the liver, lung, pleura, and spine.

Received March 14, 2007. Accepted for publication August 21, 2007.

Financial support: This study was supported by grants from the Ministry of Science and Technology, Korea and the Korea Science and Engineering Foundation through the Research Center for Resistant Cells (R13-2003-009).

Disclosure: The authors do not have any commercial interest or other association that might pose a conflict of interest.

^* Address correspondence to Dong-Min Kim, Department of Internal Medicine, Chosun University College of Medicine, 588 Seosuk-dong, Dong-gu, Gwangju 501–717, Republic of Korea. E-mail: drongkim{at}chosun.ac.kr

Authors’ addresses: Keo Woon Park, Dong-Min Kim, Chi Young Park, and Hyun Lee Kim, Department of Internal Medicine, Chosun University College of Medicine, 588 Seosuk-dong, Dong-Gu, Gwangju 501–717, Republic of Korea, Telephone: 82–62–220–3108, Fax: 82–62–234–9653, E-mail: drongkim{at}chosun.ac.kr. Sook Jin Jang, Department of Laboratory Medicine, Chosun University College of Medicine, 588 Seoseok-dong, Dong-gu, Gwang-Ju 501–717, Republic of Korea, Telephone: 82–62–220–3259, 011–614–8853, Fax: 82–62–232–2063, E-mail: sjbjang{at}chosun.ac.kr. Young Sil Choi, Mi-Yeoun Park, Division of Zoonoses, Center for Immunology and Pathology, National Institute of Health, Korea Center for Disease Control and Prevention, #5 Nokbun-Dong, Eunpyung-Gu, Seoul 122–701, Korea. Hyeon-Je Song, Department of Clincal Pathology, Gwangju Health College, Gwangju 506–701, Republic of Korea. Seung-Hyun Lee, Department of Pediatrics, Seonam University College of Medicine, Namwon, Jellabukdo 590–711, Republic of Korea.

Reprint requests: Dong-Min Kim, Division of Infectious Diseases, Department of Internal Medicine, Chosun University College of Medicine, 588 Seosuk-dong, Dong-gu, Gwangju, 501-717, Republic of Korea. E-mail: drongkim{at}chosun.ac.kr.