AJTMH ASTMH MEMBERSHIP INFORMATION: astmh@astmh.org
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am. J. Trop. Med. Hyg., 77(6), 2007, pp. 1066-1068
Copyright © 2007 by The American Society of Tropical Medicine and Hygiene

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Himeidan, Y. E.
Right arrow Articles by Yan, G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Himeidan, Y. E.
Right arrow Articles by Yan, G.
Related Collections
Right arrow Medical Entomology

SHORT REPORT


Permethrin and DDT Resistance in the Malaria Vector Anopheles arabiensis from Eastern Sudan

Yousif E. Himeidan*, Hong Chen, Fabrice Chandre, Martin J. Donnelly, AND Guiyan Yan
Faculty of Agriculture and Natural Resources, University of Kassala, New Halfa, Sudan; Program in Public Health, College of Health Sciences, University of California, Irvine, California; Institut de Recherche pour le Développement, Centre de Recherche Entomologique, Cotonou, Benin; Vector Group, Liverpool School of Tropical Medicine, Liverpool, United Kingdom

 

ABSTRACT

Assessment of resistance to DDT and permethrin insecticides and molecular detection of knockdown resistance (kdr) alleles were conducted in three populations of Anopheles arabiensis from eastern Sudan. Bioassay mortalities ranged from 96.9% to 99.6% for 4% DDT and from 98.4% to 100% for 1% permethrin. The L1014F and L1014S alleles were detected in 25 of 498 mosquitoes. The overall kdr frequencies ranged from 7.0% in the area where insecticide-treated nets were used to 3.0% in the area with agricultural insecticide use. The presence of the kdr alleles in An. arabiensis in Sudan emphasizes the need to develop appropriate resistance monitoring and management strategies for An. arabiensis.

Received June 27, 2007. Accepted for publication August 21, 2007.

Acknowledgments: We thank Hyder Abd Allah and Mohamed Omer for technical assistance during mosquito collections and bioassays, and A. Mnzava (World Health Organization [WHO] Eastern Mediterranean Region [EMRO]) for providing insecticide impregnated papers and the WHO test tubes.

Financial support: This work is supported by a grant from EMRO, WHO/TDR (Project ID SGS05/83), and National Institutes of Health grant D43 TW001505.

* Address correspondence to Yousif E. Himeidan, Climate and Human Health Research Unit, Centre for Global Health Research, Kenya Medical Research Institute, PO Box 1578, Kisumu 40100, Kenya. E-mail: yosifhimeidan{at}hotmail.com

Authors’ addresses: Yousif El-Safi Himeidan, Climate and Human Health Research Unit, Centre for Global Health Research, Kenya Medical Research Institute, PO Box 1578, Kisumu 40100, Kenya, Telephone: 254–726–413813, E-mail: yosifhimeidan{at}hotmail.com. Hong Chen and Guiyun Yan, Program in Public Health, College of Health Sciences, University of California, Irvine, CA 92697, Telephone: 949–824–0175, Fax: 949–824–0249, E-mails: guiyuny{at}uci.edu and entomail{at}gmail.com. Fabrice Chandre, Institut de Recherche pour le Développement, United de Récherche 016, Centre de Recherche Entomologique, Cotonou, 01 BP 4414 RP Cotonou, Benin, E-mail: Fabrice.Chandre{at}ird.fr. Martin James Donnelly, Vector Group, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, United Kingdom, Telephone: 44–151–705–3296, E-mail: mjames{at}liv.ac.uk.

Reprint requests: Guiyun Yan, Program in Public Health, College of Health Sciences, University of California, Irvine, CA 92697, Telephone: 949–824–0175, Fax: 949–824–0249, E-mail: guiyuny{at}uci.edu.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2007 by the American Society of Tropical Medicine and Hygiene.