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Cluster of Cases of Hantavirus Pulmonary Syndrome in Alberta, Canada

In May 2005, a cluster of four hantavirus pulmonary syndrome (HPS) cases was confirmed in Alberta, Canada. The cluster is unusual given that three cases were from a single family and involved a 7-year-old child. This is the first family cluster reported in Canada and includes one of the youngest cases of HPS reported in North America.

Received December 8, 2006. Accepted for publication July 22, 2007.

Acknowledgments: We acknowledge the contributions and the collaborative efforts of the community leaders, the community’s health director, and the community’s health staff in response to this outbreak. We also acknowledge the work and involvement of the community’s Environmental Health Officer, Simon Sihota. In addition, the authors thank T. G. Ksiazek, Centers for Disease Control and Prevention, for providing us with mouse hyperimmune serum for the IgM ELISA and positive control sera for the IgG ELISAs and thank Mike Drebot for critically reviewing the text and providing valuable assistance in the preparation of this manuscript.

^* Address correspondence to Duncan Webster, St. John Regional Hospital, P.O. Box 2100, St. John, New Brunswick, Canada E2L 4L2. E-mail: dvwebste{at}dal.ca

Authors’ addresses: Duncan Webster, Division of Infectious Diseases, Dalhousie University, QE II Health Sciences Centre, Dickson Building, 1278 Tower Road, Halifax, Nova Scotia, Canada B3H 2Y9, Telephone: 902-473-5553, Fax: 902-473-7394. Bonita Lee, Provincial Laboratory for Public Health, 2B2.01 Walter C. MacKenzie Health Sciences Centre, 8440 112 Street, Edmonton, Alberta, Canada T6G 2J2, Telephone: 780-407-3414, Fax: 780-407-8961. Ari Joffe, Department of Pediatrics, University of Alberta, 8440 112 Street, Edmonton, Alberta, Canada T6G 2R7, Telephone: 780-407-1673, Fax: 780-407-3214. Wendy Sligl, Division of Infectious Diseases, Department of Internal Medicine, University of Alberta, 8440 112 Street, Edmonton, Alberta, Canada T6G 2B7, Telephone: 780-407-8077, Fax: 780-407-7137. Daryl Dick, Allen Grolla, Heinz Feldmann, David Safronetz, and Robbin Lindsay, Zoonotic Diseases and Special Pathogens, National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, Manitoba, Canada R3E 3R2, Telephone: 204-789-2000, Fax: 204-789-2082. Wadieh Yacoub, First Nations and Inuit Health Branch, Alberta Region, 730-9700 Jasper Avenue, Edmonton, Alberta, Canada T5J 4C3, Telephone: 780-495-3391, Fax: 780-495-8070. Karen Grimsrud, Alberta Health and Wellness, 10025 Jasper Avenue, PO Box 1360, Edmonton, Alberta, Canada T5J 2N3, Telephone: 780-427-5263, Fax: 780-427-7683.

Reprint requests: Duncan Webster, Division of Infectious Diseases, St. John Regional Hospital, P.O. Box 2100, St. John, New Brunswick, Canada E2L 4L2, Telephone: 506-648-6807, Fax: 506-648-7379, E-mail: dvwebste{at}dal.ca.