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Am. J. Trop. Med. Hyg., 75(2), 2006, pp. 267-269
Copyright © 2006 by The American Society of Tropical Medicine and Hygiene

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SHORT REPORT


CONCOMITANT EARLY MUCOSAL AND CUTANEOUS LEISHMANIASIS IN BRAZIL

VIVIANE S. BOAVENTURA, VIRGINIA CAFE, JACKSON COSTA, FABIANO OLIVEIRA, ANDRE BAFICA, ANDREA ROSATO, LUIZ A. R. de FREITAS, CLAUDIA BRODSKYN, MANOEL BARRAL-NETTO, AND ALDINA BARRAL*
Centro de Pesquisas Gonçalo Moniz-Fiocruz (Fundação Oswaldo Cruz), Salvador, Bahia, Brazil; Faculdade de Medicina da Bahia (Universidade Federal da Bahia), Salvador, Bahia, Brazil; Instituto de Investigação em Imunologia, São Paulo, São Paulo, Brazil

 

ABSTRACT

Mucosal leishmaniasis (ML) is often clinically silent until reaching a highly advanced state. In this prospective study, 6 of 220 patients with early cutaneous leishmaniasis were diagnosed with mucosal involvement by otorhinolaryngological examination (a rate similar to the reported rate of late ML). Detection of early ML may represent an important strategy in preventing severe mucosal destruction in human leishmaniasis.

Received December 20, 2005. Accepted for publication April 25, 2006.

Financial support: This study was supported by CNPq (Conselho Nacional de Desenvolvimento Científico e Tecnológico) and FAPESB (Fundação de Amparo à Pesquisa do Estado da Bahia) grants. V.B. received doctorate fellowship from CAPES (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior), Brazil. A.B., J.C. and M.B-N. are senior investigators from CNPq. We thank Eliane Gocs Nascimento and members of the Centro de Referéncias para Doenças Endémicas Pirajá da Silva for support in endemic area.

Disclosure: There are no commercial or other associations that might pose a conflict of interest.

* Address correspondence to Aldina Barral, Centro de Pesquisas Gonçalo Moniz, Rua Waldemar Falcão, 121, Candeal CEP 40296-710 Salvador, Bahia, Brazil. E-mail: abarral{at}cpqgm.fiocruz.br.

Authors’ addresses: Vivane S. Boaventura, Virginia Cafe, Jackson Costa, Fabiano Oliveira, Andre Bafica, Andrea Rosato, Luiz A. R. de Freitas, Claudia Brodskyn, Manoel Barral-Netto, and Aldina Barral, Centro de Pesquisas Gonçalo Muniz Rua Waldemar Falcào, 121 Candeal, CEP 40296-710, Salvador, Bahia, Brazil.

Reprint requests: Prof. Aldina Barral, Centro de Pesquisas Gonçalo Moniz, Rua Waldemar Falcão, 121, Candeal CEP 40296-710 Salvador, Bahia, Brazil. E-mail: abarral{at}cpqgm.fiocruz.br.




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