AJTMH Transactions of the Royal Society of Tropical Medicine and Hygiene
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Am. J. Trop. Med. Hyg., 68(3), 2003, pp. 301-303
Copyright © 2003 by The American Society of Tropical Medicine and Hygiene

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CASE REPORT: SEVERE JUVENILE TYPE PARACOCCIDIOIDOMYCOSIS WITH HEPATITIS C

ANTONELLA PELLEGRINO, CLAUDIA HARTUNG DE CAPRILES, SYLVIA MAGALDI, ISRAEL MONTES DE OCA, MARÌA ELENA RUIZ, CELINA PÉREZ, AND SOFÍA MATA-ESSAYAG
Internal Medicine, Hospital Universitario de Caracas, UCV, Venezuela; Sección de Micología Médica, Instituto de Medicina Tropical, UCV, Venezuela; Instituto Anatomía Patológica, UCV, Venezuela

 

ABSTRACT

We present the case of a 34-year-old man with previous history of hepatitis C and severe juvenile type of paracoccidioidomycosis characterized by involvement of the reticuloendothelial system, eosinophilia, lung compromise (pleural effusion), retinal hemorrhage, and blood culture positive to Paracoccidioides brasiliensis. The immune evaluation showed four precipitation lines to P. brasiliensis by the double immunodiffusion test. Treatment with amphotericin B and itraconazol resulted in resolution of the disease.

Received April 9, 2002. Accepted for publication October 28, 2002.

Acknowledgments: The authors wish to thank the American Committee on Clinical Tropical Medicine and Travelers’ Health (ACCTMTH) for assistance with publication expenses.

Authors’ addresses: Antonella Pellegrino and Israel Montes de Oca, Internal Medicine, Hospital Universitario de Caracas, UCV, Venezuela. Claudia Hartung de Capriles, Sylvia Magaldi, and Celina Pérez, Sección de Micología Médica, Instituto de Medicina Tropical, UCV, Venezuela. Marìa Elena Ruiz, Instituto Anatomía Patológica, UCV, Venezuela. Sofía Mata-Essayag, Apartado Postal 47423, Caracas 1041, Venezuela, Fax: 58-212-662-10-82, E-mail: somae50{at}hotmail.com






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Copyright © 2003 by the American Society of Tropical Medicine and Hygiene.