AJTMH Transactions of the Royal Society of Tropical Medicine and Hygiene
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Am. J. Trop. Med. Hyg., 65(2), 2001, pp. 136-137
Copyright © 2001 by The American Society of Tropical Medicine and Hygiene

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American Journal of Tropical Medicine and Hygiene, Vol 65, Issue 2, 136-137
Copyright © 2001 by American Society of Tropical Medicine and Hygiene

Research Articles


Short report: Hookworm infection is associated with decreased body temperature during mild Plasmodium falciparum malaria

M Nacher, P Singhasivanon, B Traore, S Dejvorakul, W Phumratanaprapin, S Looareesuwan, and F Gay

Malaria's pyrogenic threshold seems to depend on factors such as age and transmission patterns. We studied the temperature at admission of 200 patients with mild malaria and observed that after adjusting for body mass index, the presence of other helminths, and other confounders, only hookworm-infected patients had lower fever at admission that those without hookworm infection (37.5 +/- 0.9 and 38 +/- 0.8, respectively; P < 0.001). Thus, we suggest the age dependence of the pyrogenic threshold could have been confounded by the epidemiology of iron deficiency.


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P. J. Hotez, S. Brooker, J. M. Bethony, M. E. Bottazzi, A. Loukas, and S. Xiao
Hookworm Infection
N. Engl. J. Med., August 19, 2004; 351(8): 799 - 807.
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